SCHEMBL7460840

SCHEMBL7460840

C=CC(=O)OCC(C)(C)Cc1cc2c(cc1C(=O)O)C(=O)OC2=O

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HIF1A Q16665 1/20 0.33
THRB P10828 1/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA7 P43166 1/20 0.31
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4653334 0.81 THRB (0.36) ALDH1A1TP53CYP3A4HIF1ATHRB
SCHEMBL3266665 0.80 THRB (0.44) ALDH1A1TP53CYP3A4HIF1ATHRB
SCHEMBL7474574 0.75 TSHR (0.45) ALDH1A1TP53CYP3A4HIF1ATHRB
SCHEMBL4652152 0.74 CA12 (0.30) CA12CA1CA7
SCHEMBL11500121 0.71 ALDH1A1 (0.39) ALDH1A1TP53CYP3A4CA12CA1
SCHEMBL19037330 0.68 HCAR2 (0.37) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL2059843 0.68 CA2 (0.36) ALDH1A1THRBCA12CA1CA7
SCHEMBL16909946 0.67 THRB (0.39) ALDH1A1TP53CYP3A4HIF1ATHRB
SCHEMBL64565 0.67 THRB (0.39) ALDH1A1THRBCA12CA1CA7
SCHEMBL262028 0.67 ALDH1A1 (0.59) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1197504-A1 THERMOPLASTIC POLYMER HAVING POLAR GROUP, USE THEREOF, AND UNSATURATED COMPOUNDS HAVING POLAR GROUP Mitsui Chemicals, Inc. (JP) 2002-04-17 EP disclosed