Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 5/20 | 0.33 |
| ▸ | CA7 | P43166 | 5/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474574 | 0.91 | TSHR (0.45) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL4653334 | 0.88 | THRB (0.36) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL19037330 | 0.84 | HCAR2 (0.37) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL1263541 | 0.83 | THRB (0.47) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL7460840 | 0.80 | ALDH1A1 (0.33) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL64565 | 0.80 | THRB (0.39) | THRBTSHRALDH1A1TYMSCA12 | |
| SCHEMBL7465153 | 0.80 | THRB (0.41) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL16909946 | 0.78 | THRB (0.39) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL11500121 | 0.77 | ALDH1A1 (0.39) | TSHRALDH1A1TP53HSD17B10CYP3A4 | |
| SCHEMBL2320779 | 0.76 | THRB (0.48) | THRBTSHRALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111234125-A | Aldehyde-adsorbable VOC (volatile organic compound) resin and synthesis method thereof | 烟台德邦科技有限公司 | 2020-06-05 | — | — | CN | claimed |
| US-9937104-B2 | Nanostructured antibacterial and remineralizing dental bonding agents and dental bonding systems | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2018-04-10 | — | — | US | claimed |
| US-20170202752-A1 | PROTEIN-REPELLENT DENTAL MATERIALS AND USE THEREOF IN DENTAL APPLICATIONS | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2017-07-20 | — | — | US | claimed |
| EP-3171849-A1 | PROTEIN-REPELLENT DENTAL MATERIALS AND USE THEREOF IN DENTAL APPLICATIONS | The University of Maryland, Baltimore (US) | 2017-05-31 | — | — | EP | claimed |
| US-20170112723-A1 | NANOSTRUCTURED ANTIBACTERIAL AND REMINERALIZING DENTAL BONDING AGENTS AND DENTAL BONDING SYSTEMS | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2017-04-27 | — | — | US | claimed |
| US-9554971-B2 | Nanostructured antibacterial and remineralizing dental bonding agents and dental bonding systems | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2017-01-31 | — | — | US | claimed |
| US-9290471-B2 | Dispersant, dispersion of color pigment, and photosensitive resist | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2016-03-22 | — | — | US | claimed |
| US-20160058675-A1 | NANOSTRUCTURED ANTIBACTERIAL AND REMINERALIZING DENTAL BONDING AGENTS AND DENTAL BONDING SYSTEMS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-03-03 | — | — | US | claimed |
| WO-2016015005-A1 | PROTEIN-REPELLENT DENTAL MATERIALS AND USE THEREOF IN DENTAL APPLICATIONS | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2016-01-28 | — | — | WO | claimed |
| US-20150203463-A1 | DISPERSANT, DISPERSION OF COLOR PIGMENT, AND PHOTOSENSITIVE RESIST | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2015-07-23 | — | — | US | claimed |
| EP-2811966-A1 | NANOSTRUCTURED ANTIBACTERIAL AND REMINERALIZING DENTAL BONDING AGENTS AND DENTAL BONDING SYSTEMS | University of Maryland (US) | 2014-12-17 | — | — | EP | claimed |
| US-20140148526-A1 | DENTAL BONDING AGENT AND COATING AGENT | NATIONAL TAIWAN UNIVERSITY (TW) | 2014-05-29 | — | — | US | claimed |
| US-20140050674-A1 | Method for Improving Penetration or Long Term Adhesion of Compositions to Dental Tissues and Compositions Usable in Said Method | UNIVERSITY OF OULU (FI) | 2014-02-20 | — | — | US | claimed |
| WO-2013119901-A1 | NANOSTRUCTURED ANTIBACTERIAL AND REMINERALIZING DENTAL BONDING AGENTS AND DENTAL BONDING SYSTEMS | UNIVERSITY OF MARYLAND (US) | 2013-08-15 | — | — | WO | claimed |
| WO-2012146832-A2 | A METHOD FOR IMPROVING PENETRATION OR LONG TERM ADHESION OF COMPOSITIONS TO DENTAL TISSUES AND COMPOSITIONS USABLE IN SAID METHOD | OULUN YLIOPISTO (FI) | 2012-11-01 | — | — | WO | claimed |
| EP-1986588-A2 | SELF ETCH ALL PURPOSE DENTAL COMPOSITION | Pentron Clinical Technologies, LLC (US) | 2008-11-05 | — | — | EP | claimed |
| US-20080242761-A1 | One part acrylated monomer with aromatic carboxylic anhydride functionality, multifunctional acrylate resin, diluent monomer and curing system; one step restorative dentistry; self and light curable | JIA WEITAO | 2008-10-02 | — | — | US | claimed |
| WO-2007100569-A2 | SELF ETCH ALL PURPOSE DENTAL COMPOSITION | PENTRON CLINICAL TECHNOLOGIES LLC (US) | 2007-09-07 | — | — | WO | claimed |
| US-20070197683-A1 | SELF ETCH ALL PURPOSE DENTAL COMPOSITIONS, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF | PENTRON CLINICAL TECHNOLOGIES, INC (US) | 2007-08-23 | — | — | US | claimed |
| US-20070197682-A1 | Self etch all purpose dental cement composition, method of manufacture, and method of use thereof | PENTRON CORPORATION | 2007-08-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197682-A1 | Self etch all purpose dental cement composition, method of manufacture, and method of use thereof | FHIT, COPE, ASH2L | THRB 3947/4885TSHR 4848/4885ALDH1A1 4447/4885 |
| US-20140148526-A1 | DENTAL BONDING AGENT AND COATING AGENT | PHOSPHO1, PDAP1, ITGA4 | THRB 4549/4885TSHR 4759/4885ALDH1A1 1428/4885 |
| US-20070197683-A1 | SELF ETCH ALL PURPOSE DENTAL COMPOSITIONS, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF | CAD, FHIT, ACR | THRB 1851/4885TSHR 4432/4885ALDH1A1 681/4885 |
| US-20080242761-A1 | One part acrylated monomer with aromatic carboxylic anhydride functionality, multifunctional acrylate resin, diluent monomer and curing system; one step restorative dentistry; self and light curable | CAD, TAS2R42, ACR | THRB 1701/4885TSHR 3760/4885ALDH1A1 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.