Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470465 | 0.90 | MAPK1 (0.66) | MAPK1ALDH1A1KDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL7469700 | 0.88 | EGFR (0.54) | MAPK1ALDH1A1KDM4EABCG2EGFR | |
| SCHEMBL7474806 | 0.85 | EGFR (0.52) | MAPK1ALDH1A1KDM4EEGFRBRD4 | |
| SCHEMBL7464129 | 0.85 | MAPK1 (0.69) | MAPK1KDM4ESMN1; SMN2ABCG2MEN1 | |
| SCHEMBL7474181 | 0.83 | MAPK1 (0.56) | MAPK1SMN1; SMN2EGFRHTTLMNA | |
| SCHEMBL7465161 | 0.82 | PDE5A (0.52) | MAPK1ALDH1A1SMN1; SMN2EGFRMEN1 | |
| SCHEMBL7467508 | 0.82 | MAPK1 (0.52) | MAPK1ALDH1A1SMN1; SMN2EGFRMEN1 | |
| SCHEMBL7464822 | 0.82 | ACHE (0.46) | MAPK1ALDH1A1KDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL7461530 | 0.80 | PKM (0.56) | MAPK1ALDH1A1KDM4ESMN1; SMN2EGFR | |
| SCHEMBL7463424 | 0.80 | EGFR (0.50) | MAPK1ALDH1A1KDM4EABCG2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |