Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 2/20 | 0.52 |
| ▸ | CNR2 | P34972 | 2/20 | 0.52 |
| ▸ | KMO | O15229 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 5/20 | 0.52 |
| ▸ | DRD3 | P35462 | 5/20 | 0.52 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.45 |
| ▸ | CCNK | O75909 | 1/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.44 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.44 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.44 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6497606 | 0.86 | KDM4E (0.54) | KDM4EMEN1ALDH1A1GAAHPGD | |
| SCHEMBL6498986 | 0.86 | KDM4E (0.54) | KDM4EMEN1ALDH1A1GAAHPGD | |
| SCHEMBL383016 | 0.86 | DRD2 (0.55) | KDM4EGAACNR1CNR2DRD2 | |
| SCHEMBL7471294 | 0.83 | NOS2 (0.48) | ALDH1A1CNR1DRD2DRD3PLOD2 | |
| SCHEMBL6504006 | 0.83 | TTR (0.46) | KDM4EGAACNR1CNR2DRD2 | |
| SCHEMBL6498292 | 0.82 | MEN1 (0.47) | KDM4EMEN1ALDH1A1GAAHPGD | |
| SCHEMBL6498399 | 0.82 | KDM4E (0.52) | KDM4EMEN1ALDH1A1GAAHPGD | |
| SCHEMBL7464402 | 0.81 | CNR1 (0.44) | CNR1CNR2DRD2DRD3 | |
| SCHEMBL7464438 | 0.81 | DRD2 (0.42) | CNR1CNR2DRD2DRD3PLOD2 | |
| SCHEMBL17832690 | 0.81 | HDAC1 (0.54) | KMT2ADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050059669-A1 | M-substituted benzoic acid derivatives having integrin alpha v beta 3 antagonistic activity | AJITO KEIICHI (JP) | 2005-03-17 | — | — | US | disclosed |
| EP-1229024-A1 | m-SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING INTEGRIN ALPHA-V BETA-3 ANTAGONISM | MEIJI SEIKA KAISHA LTD. (JP) | 2002-08-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059669-A1 | M-substituted benzoic acid derivatives having integrin alpha v beta 3 antagonistic activity | ITGAV, ITGB3, ITGA4 | KDM4E 945/4885MEN1 1713/4885ALDH1A1 1967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.