Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 4/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474960 | 0.90 | MAPT (0.43) | WDR5KMT2AHTR6EGFRMAPK1 | |
| SCHEMBL7466158 | 0.88 | HTR6 (0.55) | HTR6EGFRMAPK1ALDH1A1LMNA | |
| SCHEMBL7464822 | 0.87 | ACHE (0.46) | KMT2AHTR6EGFRMAPK1ALDH1A1 | |
| SCHEMBL7471116 | 0.86 | HTT (0.52) | WDR5KMT2AHTR6MAPT | |
| SCHEMBL7470023 | 0.85 | HTR6 (0.44) | WDR5KMT2AHTR6MAPK1LMNA | |
| SCHEMBL7467406 | 0.85 | MAPT (0.44) | WDR5KMT2AHTR6EGFRMAPK1 | |
| SCHEMBL7469830 | 0.85 | HTR6 (0.44) | WDR5KMT2AHTR6EGFRMAPK1 | |
| SCHEMBL7471400 | 0.85 | MAPT (0.42) | WDR5KMT2AHTR6EGFRALDH1A1 | |
| SCHEMBL7467064 | 0.84 | HTR6 (0.52) | HTR6EGFRMAPK1ALDH1A1LMNA | |
| SCHEMBL7470628 | 0.84 | HTR6 (0.48) | HTR6EGFRMAPK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |