Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 5/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471400 | 0.95 | MAPT (0.42) | MAPTLMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7461647 | 0.91 | EGFR (0.48) | MAPTLMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7468426 | 0.90 | WDR5 (0.42) | MAPTLMNAALDH1A1HTR6EGFR | |
| SCHEMBL7466158 | 0.88 | HTR6 (0.55) | MAPTLMNAALDH1A1SMN1; SMN2HTR6 | |
| SCHEMBL7464822 | 0.87 | ACHE (0.46) | MAPTALDH1A1SMN1; SMN2HTR6EGFR | |
| SCHEMBL7461677 | 0.87 | HTR1A (0.46) | LMNAHTR6EGFRHTR1ASLC6A2 | |
| SCHEMBL7469830 | 0.87 | HTR6 (0.44) | MAPTLMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7469384 | 0.86 | HTT (0.46) | MAPTLMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7470488 | 0.85 | HTR6 (0.44) | MAPTLMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7467406 | 0.85 | MAPT (0.44) | MAPTLMNAGAAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |