Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.40 |
| ▸ | ADK | P55263 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552777 | 0.92 | ALDH1A1 (0.45) | TSHRALDH1A1SMN1; SMN2XIAPGSK3B | |
| SCHEMBL8603405 | 0.92 | TSHR (0.42) | TSHRALDH1A1SMN1; SMN2XIAPGSK3B | |
| SCHEMBL8557746 | 0.87 | TSHR (0.45) | TSHRALDH1A1SMN1; SMN2XIAPGSK3B | |
| SCHEMBL7465291 | 0.87 | TSHR (0.46) | TSHRALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL8604456 | 0.86 | TSHR (0.45) | TSHRALDH1A1SMN1; SMN2XIAPGID4 | |
| SCHEMBL7469178 | 0.85 | LMNA (0.42) | TSHRALDH1A1SMN1; SMN2TP53KMT2A | |
| SCHEMBL7475653 | 0.85 | ALDH1A1 (0.42) | TSHRALDH1A1SMN1; SMN2GSK3BADK | |
| SCHEMBL8555175 | 0.85 | FAAH (0.50) | TSHRALDH1A1SMN1; SMN2XIAPGID4 | |
| SCHEMBL7465815 | 0.84 | TSHR (0.40) | TSHRALDH1A1SMN1; SMN2XIAPTP53 | |
| SCHEMBL8604688 | 0.84 | GSK3B (0.40) | TSHRALDH1A1SMN1; SMN2XIAPGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |