Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.51 |
| ▸ | CLK1 | P49759 | 1/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.51 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 9/20 | 0.49 |
| ▸ | PIM2 | Q9P1W9 | 9/20 | 0.49 |
| ▸ | IGF1R | P08069 | 2/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CISD1 | Q9NZ45 | 4/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465304 | 0.83 | PIM1 (0.73) | PIM1PIM2IGF1RAKR1B1GSK3B | |
| SCHEMBL7465302 | 0.83 | PIM1 (0.73) | PIM1PIM2IGF1RAKR1B1GSK3B | |
| SCHEMBL7464574 | 0.81 | PIM1 (0.68) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL7463867 | 0.79 | PIM1 (0.68) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL7466029 | 0.77 | CSNK2A1 (0.71) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL7459912 | 0.77 | GSK3B (0.71) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL9433321 | 0.77 | MMP13 (0.61) | AKR1B1MAOAMAOBADAMTS5 | |
| SCHEMBL4156417 | 0.76 | CSNK2A2 (0.65) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL7466320 | 0.74 | PIM1 (0.73) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL3787295 | 0.73 | IGF1R (0.71) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214305-A1 | BENZYLIDENE-THIAZOLIDINEDIONES AND ANALOGUES AND THEIR USE IN THE TREATMENT OF INFLAMMATION | Maxia Pharmaceuticals, Inc. (US) | 2002-06-19 | — | — | EP | claimed |
| WO-2001016123-A1 | BENZYLIDENE-THIAZOLIDINEDIONES AND ANALOGUES AND THEIR USE IN THE TREATMENT OF INFLAMMATION | MAXIA PHARMACEUTICALS, INC. (US) | 2001-03-08 | — | — | WO | claimed |