Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892282 | 0.95 | NAMPT (0.41) | MEN1KMT2AMAPTKDM4ETDP1 | |
| SCHEMBL7457631 | 0.86 | KMT2A (0.51) | MEN1KMT2AMAPTKDM4ETDP1 | |
| SCHEMBL8893137 | 0.84 | ADORA2A (0.49) | MEN1KMT2AMAPTKDM4ETDP1 | |
| SCHEMBL7458570 | 0.83 | NAMPT (0.43) | MEN1KMT2ANAMPTCYP2C19POLB | |
| SCHEMBL27505327 | 0.80 | RORC (0.42) | — | |
| SCHEMBL8892340 | 0.78 | MEN1 (0.42) | MEN1KMT2AMAPTKDM4ETDP1 | |
| SCHEMBL8892614 | 0.77 | HPGD (0.43) | MEN1KMT2ATDP1NAMPTCYP2D6 | |
| SCHEMBL7462288 | 0.76 | LMNA (0.40) | MEN1KMT2AMAPTTDP1NAMPT | |
| SCHEMBL7458575 | 0.76 | NAMPT (0.42) | MEN1KMT2ANAMPTCYP2C19POLB | |
| SCHEMBL7314568 | 0.76 | F10 (0.48) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697408-B1 | 1 substituted-phenyl-oxazolidene-2-one derivatives and their use as adhesion-receptor antagonists | MERCK PATENT GMBH (DE) | 2002-01-23 | — | — | EP | disclosed |
| EP-0697408-A1 | 1 substituted-phenyl-oxazolidene-2-one derivatives and their use as adhesion-receptor antagonists | MERCK PATENT GmbH (DE) | 1996-02-21 | — | — | EP | disclosed |