Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7455413 | 0.92 | SIGMAR1 (0.42) | MEN1KMT2ASIGMAR1CA1CA2 | |
| SCHEMBL8892614 | 0.87 | HPGD (0.43) | MEN1KMT2ANAMPTITGB3ITGA2B | |
| SCHEMBL7462288 | 0.85 | LMNA (0.40) | MEN1KMT2ANAMPTNTSR1MAPT | |
| SCHEMBL7464219 | 0.84 | SIGMAR1 (0.41) | MEN1KMT2ASIGMAR1CA1CA2 | |
| SCHEMBL8891141 | 0.84 | ITGB3 (0.40) | MEN1KMT2ASIGMAR1CA1CA2 | |
| Water SCHEMBL7461996 | 0.83 | SIGMAR1 (0.41) | MEN1KMT2ASIGMAR1CA1CA2 | |
| Ether SCHEMBL7461990 | 0.81 | SIGMAR1 (0.39) | MEN1KMT2ASIGMAR1NAMPTITGB3 | |
| SCHEMBL8891751 | 0.81 | FNTA (0.45) | ITGB3ITGA2B | |
| SCHEMBL8891722 | 0.80 | ITGB3 (0.36) | MEN1KMT2ASIGMAR1CA1CA2 | |
| SCHEMBL8892077 | 0.80 | ITGB3 (0.43) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |