Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465489 | 0.95 | MEN1 (0.42) | NAMPTATMKMT2AMEN1POLB | |
| SCHEMBL8893137 | 0.87 | ADORA2A (0.49) | ATMKMT2AMEN1CTSKKDM4E | |
| SCHEMBL7458570 | 0.85 | NAMPT (0.43) | NAMPTKMT2AMEN1POLBCYP2C19 | |
| SCHEMBL7457631 | 0.84 | KMT2A (0.51) | ATMKMT2AMEN1CTSKKDM4E | |
| SCHEMBL7458396 | 0.80 | GRM2 (0.43) | ADORA2A | |
| SCHEMBL8892340 | 0.78 | MEN1 (0.42) | NAMPTKMT2AMEN1KDM4EMAPT | |
| SCHEMBL7458575 | 0.77 | NAMPT (0.42) | NAMPTKMT2AMEN1POLBCYP2C19 | |
| SCHEMBL7314568 | 0.77 | F10 (0.48) | NAMPT | |
| SCHEMBL8892614 | 0.77 | HPGD (0.43) | NAMPTKMT2AMEN1TDP1CYP2D6 | |
| SCHEMBL7462288 | 0.76 | LMNA (0.40) | NAMPTKMT2AMEN1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |