Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 12/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 12/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 12/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 12/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 12/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 12/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 8/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 8/20 | 0.41 |
| ▸ | GABRP | O00591 | 6/20 | 0.41 |
| ▸ | GABRD | O14764 | 6/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.41 |
| ▸ | GABRE | P78334 | 6/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466678 | 0.88 | GABRA1 (0.34) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL7460674 | 0.81 | GABRA1 (0.37) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL7467746 | 0.80 | P4HB (0.33) | — | |
| SCHEMBL7469597 | 0.77 | PYGL (0.32) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL7470446 | 0.75 | SYK (0.35) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL7463771 | 0.75 | GABRA1 (0.36) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL7464585 | 0.75 | P4HB (0.31) | — | |
| SCHEMBL7461868 | 0.74 | ABCB1 (0.32) | KDM4ENPC1ALDH1A1 | |
| SCHEMBL6851179 | 0.74 | ADH1A (0.35) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL7463040 | 0.73 | ADH1A (0.33) | ADH1AKITFLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656360-B1 | TRIFLUOROMETHYLPYRROLOINDOLE CARBOXYLIC ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN SEIYAKU KK (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-5629430-A | ANTICARCINOGENIC AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0656360-A1 | TRIFLUOROMETHYLPYRROLOINDOLE CARBOXYLIC ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1995-06-07 | — | — | EP | disclosed |