Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.46 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.42 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.42 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469643 | 0.81 | CDK2 (0.48) | GAAADORA2BADORA1MAP4K4ADORA3 | |
| SCHEMBL7463567 | 0.78 | SRC (0.56) | GAAMAPTALDH1A1SYKSRC | |
| SCHEMBL19833693 | 0.74 | ALDH1A1 (0.53) | GAAMAPTALDH1A1HSD17B10ADORA1 | |
| SCHEMBL7147816 | 0.71 | ADORA2A (0.52) | MAPTALDH1A1HSD17B10ADORA2BADORA1 | |
| SCHEMBL19427367 | 0.69 | KDR (0.53) | MAPTALDH1A1ADORA1CLK4JAK2 | |
| SCHEMBL7464447 | 0.68 | PIK3CA (0.62) | GAAALDH1A1HSD17B10AURKBSYK | |
| SCHEMBL19427395 | 0.68 | SYK (0.56) | ADORA1SYKCDK2AURKA | |
| SCHEMBL27608176 | 0.66 | ADORA2B (0.50) | GAAALDH1A1ADORA2BADORA1MAP4K4 | |
| SCHEMBL27589833 | 0.65 | ADORA2B (0.53) | GAAALDH1A1ADORA2BADORA1MAP4K4 | |
| SCHEMBL7475349 | 0.65 | ALDH1A1 (0.42) | GAAMAPTALDH1A1HSD17B10ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233461-B2 | 4,5,6-Substituted-2-pyrimidinamines | AMERICAN CYANAMID CO (US) | 2002-05-29 | — | — | EP | disclosed |