Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7050641 | 0.88 | OPRK1 (0.42) | OPRK1NR1H2USP2MAPK1CDK4 | |
| SCHEMBL7466043 | 0.88 | OPRK1 (0.43) | OPRK1KDM4EUSP2MAPK1CDK4 | |
| SCHEMBL7469676 | 0.87 | RBP4 (0.36) | CDK4CCND1 | |
| SCHEMBL7470661 | 0.86 | OPRK1 (0.42) | OPRK1MAPK1CDK4CCND1HTT | |
| SCHEMBL7054704 | 0.82 | ALDH1A1 (0.45) | OPRK1KDM4ETP53MAPK1HSD17B10 | |
| SCHEMBL7466392 | 0.81 | OPRK1 (0.47) | OPRK1NR1H2KDM4EUSP2TP53 | |
| SCHEMBL7468705 | 0.80 | KDM4E (0.41) | NR1H2KDM4EUSP2TP53MAPK1 | |
| SCHEMBL382148 | 0.79 | MAPT (0.46) | KDM4EUSP2MAPK1RECQLHSD17B10 | |
| SCHEMBL7051584 | 0.75 | KDM4E (0.37) | KDM4ECDK4CCND1MEN1MAPT | |
| SCHEMBL7463190 | 0.73 | GCK (0.40) | RECQLCDK4CCND1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |