Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.35 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051584 | 0.87 | KDM4E (0.37) | NR3C2CDK4CCND1MAPK8CAMKK1 | |
| SCHEMBL7469676 | 0.85 | RBP4 (0.36) | CDK4CCND1 | |
| SCHEMBL7470661 | 0.85 | OPRK1 (0.42) | CDK4CCND1ALDH1A1RAB9AMAPT | |
| SCHEMBL7053331 | 0.82 | HCAR3 (0.40) | CDK4CCND1ALDH1A1LMNARAB9A | |
| SCHEMBL6497602 | 0.81 | MEN1 (0.49) | MYCNR4A1CDK4CCND1RECQL | |
| SCHEMBL7467119 | 0.81 | GAA (0.40) | CDK4CCND1ALDH1A1MEN1KMT2A | |
| SCHEMBL7468832 | 0.80 | TDP1 (0.39) | EPHX2RECQLALDH1A1MEN1KMT2A | |
| SCHEMBL7461760 | 0.78 | ITGB3 (0.48) | — | |
| SCHEMBL382582 | 0.78 | USP2 (0.40) | CDK4CCND1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7463196 | 0.77 | PPARA (0.41) | EPHX2MAPK8AVPR2DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |