Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8605543 | 0.92 | NPFFR1 (0.36) | KCNH2MAPK1ALDH1A1TSHRGAA | |
| SCHEMBL7470321 | 0.88 | NPFFR1 (0.36) | KCNH2MAPK1ALDH1A1TSHRNPC1 | |
| Hydrochloric Acid SCHEMBL7462740 | 0.87 | NPFFR1 (0.36) | KCNH2MAPK1ALDH1A1TSHRNPC1 | |
| SCHEMBL7471326 | 0.86 | MEN1 (0.39) | KCNH2MAPK1ALDH1A1TSHRTP53 | |
| SCHEMBL8554026 | 0.86 | KCNH2 (0.41) | KCNH2MAPK1ALDH1A1RAB9ATP53 | |
| SCHEMBL8556736 | 0.86 | SIRT2 (0.41) | KCNH2SIRT2SIRT1MAPK1ALDH1A1 | |
| SCHEMBL8604248 | 0.85 | ALDH1A1 (0.38) | KCNH2SIRT2SIRT1MAPK1ALDH1A1 | |
| SCHEMBL8555600 | 0.85 | SIRT2 (0.43) | GSK3BKCNH2SIRT2SIRT1MAPK1 | |
| SCHEMBL8557110 | 0.84 | ALDH1A1 (0.36) | KCNH2SIRT2SIRT1MAPK1ALDH1A1 | |
| SCHEMBL8551402 | 0.82 | MEN1 (0.39) | KCNH2MAPK1ALDH1A1TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-B1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO MCNEIL PHARM INC (US) | 2002-12-18 | — | — | EP | claimed |
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | claimed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | claimed |