Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7476670 | 0.88 | SLC6A12 (0.48) | — | |
| SCHEMBL7474726 | 0.87 | ALDH1A1 (0.57) | ALDH1A1KDM4EPOLBHPGDTDP1 | |
| Hydrochloric Acid SCHEMBL7468764 | 0.87 | SLC6A12 (0.48) | — | |
| SCHEMBL8720397 | 0.82 | KDM4E (0.54) | ALDH1A1KDM4EPOLBTDP1TSHR | |
| SCHEMBL7478560 | 0.80 | ALDH1A1 (0.58) | ALDH1A1KDM4EPOLBHPGDTDP1 | |
| SCHEMBL7473981 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KDM4E | |
| SCHEMBL7473056 | 0.78 | ALDH1A1 (0.57) | ALDH1A1KDM4EPOLBHPGDTDP1 | |
| SCHEMBL8173592 | 0.74 | ALDH1A1 (0.62) | ALDH1A1KDM4ETDP1TSHRSMN1; SMN2 | |
| SCHEMBL7471275 | 0.74 | SLC6A1 (0.55) | — | |
| Acetic Acid SCHEMBL7473986 | 0.74 | SLC6A1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0851865-B1 | 12H-Dibenzo[d,g][1,3]dioxocine derivatives | NOVO NORDISK AS (DK) | 2002-07-17 | — | — | EP | disclosed |
| US-6017915-A | Heterocyclic compounds | NOVO NORDISK A/S (DK) | 2000-01-25 | — | — | US | disclosed |
| US-5972925-A | 1-(3-(2-CHLORO-12H-DIBENZO(D,G)(1,3,6)DIOXAZOCIN-12-YL)-1-PROP YL)-3-PIPERIDINECARBOXYLIC ACID, FOR EXAMPLE; TREATING NEUROGENIC PAIN (IN WHICH C-FIBERS PLAY A ROLE) OR INFLAMMATION SUCH AS MIGRAINE OR DIABETIC NEUROPATHY | NOVO NORDISK A/S (DK) | 1999-10-26 | — | — | US | disclosed |