Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466818 | 0.82 | ALDH1A1 (0.58) | KDM4EALDH1A1TDP1POLBL3MBTL1 | |
| SCHEMBL8173592 | 0.81 | ALDH1A1 (0.62) | KDM4EALDH1A1TDP1L3MBTL1ATM | |
| SCHEMBL8169494 | 0.79 | LMNA (0.59) | KDM4EALDH1A1TDP1L3MBTL1ATM | |
| SCHEMBL8716102 | 0.79 | SLC6A1 (0.65) | — | |
| SCHEMBL8859046 | 0.79 | SLC6A1 (0.57) | KDM4EALDH1A1TDP1POLBTSHR | |
| SCHEMBL7474726 | 0.78 | ALDH1A1 (0.57) | KDM4EALDH1A1TDP1POLBL3MBTL1 | |
| SCHEMBL8196738 | 0.78 | KDM4E (0.55) | KDM4EALDH1A1TDP1POLB | |
| SCHEMBL8859050 | 0.78 | ALDH1A1 (0.53) | KDM4EALDH1A1TDP1L3MBTL1ATM | |
| SCHEMBL9085531 | 0.78 | ALDH1A1 (0.53) | KDM4EALDH1A1TDP1L3MBTL1ATM | |
| SCHEMBL8194970 | 0.77 | ALDH1A1 (0.59) | KDM4EALDH1A1TDP1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825984-A1 | NOVEL METHOD | NOVO NORDISK A/S (DK) | 1998-03-04 | — | — | EP | disclosed |
| WO-1996031471-A1 | NOVEL METHOD | NOVO NORDISK A/S (DK) | 1996-10-10 | — | — | WO | disclosed |