Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TRAF6 | Q9Y4K3 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | TP53 | P04637 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472833 | 0.87 | MAPT (0.48) | TRAF6MAPTTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL7468017 | 0.87 | HDAC6 (0.45) | L3MBTL1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7468006 | 0.84 | MAPT (0.46) | MAPTTP53ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7563746 | 0.83 | MAPT (0.49) | L3MBTL1MAPTTP53ALDH1A1LMNA | |
| SCHEMBL7472637 | 0.82 | MEN1 (0.40) | L3MBTL1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7461911 | 0.81 | MAPT (0.44) | L3MBTL1MAPTTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL7468103 | 0.81 | GAA (0.44) | MAPTTP53ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7472835 | 0.80 | SMN1; SMN2 (0.43) | L3MBTL1MAPTSMN1; SMN2 | |
| Iodide SCHEMBL7464178 | 0.80 | MAPT (0.37) | MAPTTP53ALDH1A1SMN1; SMN2USP2 | |
| SCHEMBL7467945 | 0.79 | AKR1B1 (0.39) | MAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |