Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.39 |
| ▸ | F10 | P00742 | 5/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | FADS1 | O60427 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466423 | 0.84 | ITGB3 (0.51) | MAOAITGB3ITGA2BF10PRSS1 | |
| SCHEMBL4669144 | 0.82 | L3MBTL1 (0.48) | MAOAITGB3ITGA2BF10PRSS1 | |
| SCHEMBL4669143 | 0.82 | L3MBTL1 (0.48) | MAOAITGB3ITGA2BF10PRSS1 | |
| SCHEMBL7462745 | 0.81 | ITGB3 (0.39) | MAOAITGB3ITGA2BF10PRSS1 | |
| SCHEMBL2322579 | 0.78 | GRM2 (0.54) | F10GRM2FADS1 | |
| SCHEMBL4670666 | 0.78 | GRM2 (0.54) | F10GRM2FADS1 | |
| SCHEMBL4669702 | 0.78 | GRM2 (0.54) | F10GRM2FADS1 | |
| SCHEMBL7460584 | 0.77 | GRM2 (0.52) | MAOAGRM2FADS1 | |
| SCHEMBL7461978 | 0.77 | MAOA (0.44) | MAOAITGB3ITGA2BF10PRSS1 | |
| SCHEMBL8894588 | 0.77 | ITGB3 (0.42) | ITGB3ITGA2BF10PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697408-B1 | 1 substituted-phenyl-oxazolidene-2-one derivatives and their use as adhesion-receptor antagonists | MERCK PATENT GMBH (DE) | 2002-01-23 | — | — | EP | claimed |
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | claimed |
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |