Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14665548 | 0.87 | MMP2 (0.53) | RHEBKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL7471440 | 0.86 | CHEK2 (0.45) | KDM4EALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL1170648 | 0.79 | KDM4E (0.61) | RHEBKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL8610747 | 0.79 | NPBWR1 (0.60) | RHEBKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL7470449 | 0.78 | MAPT (0.39) | ALDH1A1NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL5952721 | 0.77 | RHEB (0.46) | RHEBKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL18229582 | 0.77 | HDAC6 (0.66) | HDAC6 | |
| Hydrochloric Acid SCHEMBL7466334 | 0.77 | MAPT (0.38) | PKMHDAC6L3MBTL1 | |
| SCHEMBL25318263 | 0.75 | KDM4E (0.75) | RHEBKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL29906102 | 0.75 | KDM4E (0.75) | RHEBKDM4EALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-5852011-A | Benzimidazole derivatives | MITSUI CHEMICALS, INC. (JP) | 1998-12-22 | — | — | US | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |