Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 3/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464891 | 0.84 | MAPT (0.40) | MAPTPKMMAPK1L3MBTL1THRB | |
| Hydrochloric Acid SCHEMBL7466334 | 0.84 | MAPT (0.38) | MAPTPKMMAPK1HDAC6L3MBTL1 | |
| SCHEMBL8987545 | 0.82 | MMP2 (0.49) | MAPTL3MBTL1RAB9ANPC1 | |
| SCHEMBL7471440 | 0.80 | CHEK2 (0.45) | MAPTHDAC6RAB9AGAASMN1; SMN2 | |
| SCHEMBL8987680 | 0.80 | MAPT (0.51) | MAPTL3MBTL1THRBRAB9AIRAK4 | |
| SCHEMBL7463872 | 0.79 | MAPT (0.39) | MAPTPKMMAPK1HDAC6L3MBTL1 | |
| SCHEMBL7467865 | 0.78 | RHEB (0.45) | PKMHDAC6L3MBTL1RAB9AIRAK4 | |
| SCHEMBL7473157 | 0.78 | MAPT (0.43) | MAPTPKMMAPK1L3MBTL1THRB | |
| SCHEMBL7467214 | 0.78 | MAPT (0.38) | MAPTPKMMAPK1L3MBTL1THRB | |
| SCHEMBL18229582 | 0.75 | HDAC6 (0.66) | HDAC6HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |