Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | CASP1 | P29466 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.48 |
| ▸ | CASP7 | P55210 | 2/20 | 0.48 |
| ▸ | HBB | P68871 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2257756 | 0.91 | ALDH1A1 (0.56) | ALDH1A1CYP3A4HSD17B10CASP1HIF1A | |
| SCHEMBL2257102 | 0.91 | ALDH1A1 (0.56) | ALDH1A1CYP3A4HSD17B10CASP1HIF1A | |
| SCHEMBL2252105 | 0.91 | ALDH1A1 (0.50) | ALDH1A1CYP3A4HSD17B10CASP1HIF1A | |
| SCHEMBL129202 | 0.77 | — | — | |
| SCHEMBL145891 | 0.77 | ALDH1A1 (0.77) | ALDH1A1CYP3A4HSD17B10CASP1HIF1A | |
| SCHEMBL29367325 | 0.77 | ALDH1A1 (0.77) | ALDH1A1CYP3A4HSD17B10CASP1HIF1A | |
| SCHEMBL559813 | 0.75 | — | — | |
| SCHEMBL70257 | 0.75 | — | — | |
| Fluoride SCHEMBL27620141 | 0.74 | ALDH1A1 (0.72) | ALDH1A1CYP3A4HSD17B10CASP1HIF1A | |
| SCHEMBL645484 | 0.73 | CYP1A2 (0.59) | ALDH1A1CYP3A4HSD17B10TDP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 717 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048893-A1 | Substituted arylalkanoic acid derivatives and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2010-02-25 | — | — | US | claimed |
| EP-2006271-A9 | SUBSTITUTED BICYCLIC CYCLIC DERIVATIVE AND USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2009-07-29 | — | — | EP | claimed |
| US-20090054401-A1 | Substituted bicyclic derivatives and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-02-26 | — | — | US | claimed |
| EP-2006271-A2 | SUBSTITUTED BICYCLIC CYCLIC DERIVATIVE AND USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2008-12-24 | — | — | EP | claimed |
| CN-118339214-A | Coating composition | PPG工业俄亥俄公司 | 2024-07-12 | — | — | CN | disclosed |
| US-12018110-B2 | Acrylic polyester resin and an aqueous coating composition containing the same | PPG INDUSTRIES OHIO, INC. (US) | 2024-06-25 | — | — | US | disclosed |
| EP-4382545-A2 | AN ACRYLIC POLYESTER RESIN AND AN AQUEOUS COATING COMPOSITION CONTAINING THE SAME | PPG Industries Ohio, Inc. (US) | 2024-06-12 | — | — | EP | disclosed |
| CN-115678377-B | Acrylic polyester resin and aqueous coating composition containing same | PPG工业俄亥俄公司 | 2024-05-28 | — | — | CN | disclosed |
| EP-4372020-A2 | AN ACRYLIC POLYESTER RESIN AND AN AQUEOUS COATING COMPOSITION CONTAINING THE SAME | PPG Industries Ohio, Inc. (US) | 2024-05-22 | — | — | EP | disclosed |
| US-20240158650-A1 | A COATING COMPOSITION | PPG COATINGS EUROPE B.V. (NL) | 2024-05-16 | — | — | US | disclosed |
| US-11981764-B2 | Acrylic polyester resin and an aqueous coating composition containing the same | PPG INDUSTRIES OHIO, INC. (US) | 2024-05-14 | — | — | US | disclosed |
| WO-2024074813-A1 | A COMPOUND AND ITS USE FOR DETECTING A DISEASE IN THE EXHALED BREATH OF A SUBJECT | OWLSTONE MEDICAL LIMITED (GB) | 2024-04-11 | — | — | WO | disclosed |
| WO-1995006030-A1 | HYDROXYETHYLAMINO SULPHONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1995-03-02 | — | — | WO | disclosed |
| US-5374697-A | Selected novel sulfonium compounds particularly suitable as initiators for the thermal cure of cationically polymerisable materials | CIBA-GEIGY CORPORATION (US) | 1994-12-20 | — | — | US | disclosed |
| US-5296567-A | Using stable initiator | CIBA-GEIGY CORPORATION (US) | 1994-03-22 | — | — | US | disclosed |
| EP-0580552-A1 | Selected new sulphonium compounds, particularly suitable as initiators for the thermal curing of cationically polymerisable materials | CIBA-GEIGY AG (CH) | 1994-01-26 | — | — | EP | disclosed |
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |
| EP-0508952-A2 | Epoxy resin blends, especially for the preparation of storable prepregs | CIBA-GEIGY AG (CH) | 1992-10-14 | — | — | EP | disclosed |
| EP-0508951-A2 | Heat curable composition | CIBA-GEIGY AG (CH) | 1992-10-14 | — | — | EP | disclosed |
| EP-0452263-A2 | Epoxy resin mixtures containing an iron-arene complex and a particular amine | CIBA-GEIGY AG (CH) | 1991-10-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054401-A1 | Substituted bicyclic derivatives and use thereof | LTB4R2, LTC4S, LTB4R | ALDH1A1 1731/4885CYP3A4 1212/4885HSD17B10 868/4885 |
| US-20100048893-A1 | Substituted arylalkanoic acid derivatives and use thereof | CYSLTR1, CYSLTR2, LTB4R2 | ALDH1A1 996/4885CYP3A4 838/4885HSD17B10 648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.