Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603773 | 0.86 | PPARG (0.44) | PPARGTP53LMNA | |
| SCHEMBL8604513 | 0.80 | TSHR (0.44) | PPARGTP53LMNA | |
| SCHEMBL7468173 | 0.80 | PPARG (0.41) | PPARG | |
| SCHEMBL8603793 | 0.78 | ALDH1A1 (0.45) | PPARGTP53LMNA | |
| SCHEMBL8554097 | 0.78 | ALDH1A1 (0.45) | PPARGTP53 | |
| SCHEMBL8557139 | 0.78 | TP53 (0.42) | PPARGTP53 | |
| SCHEMBL8557727 | 0.77 | GSK3B (0.47) | PPARGTP53LMNA | |
| SCHEMBL7476790 | 0.75 | TSHR (0.45) | PPARGTP53 | |
| SCHEMBL8551614 | 0.75 | TSHR (0.43) | PPARGTP53 | |
| SCHEMBL8604584 | 0.75 | KDM4E (0.45) | PPARGTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-B1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO MCNEIL PHARM INC (US) | 2002-12-18 | — | — | EP | disclosed |