Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | RAB9A | P51151 | 7/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.61 |
| ▸ | RELA | Q04206 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18074821 | 0.80 | LTA4H (1.00) | LTA4HALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL7470299 | 0.79 | MGLL (0.62) | LTA4HALDH1A1RAB9ANPC1MAPT | |
| Hydrochloric Acid SCHEMBL7470042 | 0.78 | MGLL (0.61) | LTA4HALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL2907964 | 0.77 | ALDH1A1 (1.00) | LTA4HALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL13131237 | 0.77 | LTA4H (0.77) | LTA4HALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL44869 | 0.77 | ALDH1A1 (1.00) | LTA4HALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL7463271 | 0.77 | RAB9A (0.60) | LTA4HALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL29427805 | 0.76 | NPC1 (0.70) | ALDH1A1RAB9ANPC1MAPTMEN1 | |
| SCHEMBL18029565 | 0.76 | NPC1 (0.70) | ALDH1A1RAB9ANPC1MAPTMEN1 | |
| SCHEMBL1820346 | 0.75 | ALDH1A1 (0.76) | ALDH1A1RAB9ANPC1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871619-B1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMA (US) | 2002-11-06 | — | — | EP | disclosed |
| EP-0871619-A1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997024343-A1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1997-07-10 | — | — | WO | disclosed |