SCHEMBL8552816

SCHEMBL8552816

COc1ccccc1CN1C(=O)C(CCOc2ccc(C(C)N=C(N)N)cc2)Oc2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 19/20 0.46
XIAP P98170 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8557722 0.88 GSK3B (0.45) PPARG
SCHEMBL8595841 0.84 TSHR (0.44) PPARG
SCHEMBL8556732 0.82 SIRT2 (0.41) PPARG
SCHEMBL8555598 0.81 SIRT2 (0.43) PPARG
SCHEMBL8603773 0.79 PPARG (0.44) PPARG
SCHEMBL8551158 0.78 TSHR (0.38) XIAP
SCHEMBL7468634 0.76 HTT (0.54) PPARGXIAP
SCHEMBL7465812 0.76 TSHR (0.41) XIAP
SCHEMBL8555937 0.75 TSHR (0.48) XIAP
SCHEMBL7468173 0.74 PPARG (0.41) PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0869949-A1 BENZOXAZINE ANTIMICROBIAL AGENTS ORTHO PHARMACEUTICAL CORPORATION (US) 1998-10-14 EP disclosed
WO-1997017333-A1 BENZOXAZINE ANTIMICROBIAL AGENTS ORTHO PHARMACEUTICAL CORPORATION (US) 1997-05-15 WO disclosed