Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5108700 | 0.85 | PLA2G4B (0.55) | PPARDCA2CAMK2ASRD5A2PLA2G4B | |
| SCHEMBL11683055 | 0.83 | PLA2G4B (0.61) | CA2CAMK2ASRD5A2PLA2G4BAKR1B1 | |
| SCHEMBL2763189 | 0.83 | PLA2G4B (0.57) | PPARDCA2CAMK2ASRD5A2PLA2G4B | |
| SCHEMBL7750520 | 0.82 | PLA2G4B (0.60) | PPARDSRD5A2PLA2G4BFFAR1LMNA | |
| SCHEMBL11155906 | 0.82 | CA2 (0.54) | PPARDCA2CAMK2ASRD5A2PLA2G4B | |
| SCHEMBL11684213 | 0.82 | PLA2G4B (0.69) | CA2CAMK2APLA2G4BAKR1B1FFAR1 | |
| SCHEMBL9832704 | 0.82 | ALOX15 (0.63) | PPARDCA2CAMK2ASRD5A2PLA2G4B | |
| SCHEMBL11351141 | 0.80 | CA2 (0.52) | PPARDCA2CAMK2ASRD5A2PLA2G4B | |
| SCHEMBL11209134 | 0.80 | CA2 (0.52) | PPARDCA2CAMK2ASRD5A2PLA2G4B | |
| SCHEMBL503308 | 0.80 | PLA2G4B (0.58) | CA2CAMK2APLA2G4BPOLBRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077701-A4 | ANTI-VIRAL COMPOUNDS | LILLY CO ELI (US) | 2002-03-20 | — | — | EP | disclosed |
| CN-1292697-A | Anti-viral compound | LILLY CO ELI (US) | 2001-04-25 | — | — | CN | disclosed |
| EP-0661279-B1 | Polyaminated ligands, metal complexes, process for their preparation and diagnostic and therapeutic applications | GUERBET SA (FR) | 2001-03-07 | — | — | EP | disclosed |
| EP-1077701-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059587-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-11-25 | — | — | WO | disclosed |
| EP-0661279-A1 | Polyaminated ligands, metal complexes, process for their preparation and diagnostic and therapeutic applications | GUERBET S.A. (FR) | 1995-07-05 | — | — | EP | disclosed |