SCHEMBL11209134

SCHEMBL11209134

O=C(O)Cc1ccc(OCF)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.52
CAMK2A Q9UQM7 1/20 0.52
SRD5A2 P31213 2/20 0.50
PLA2G4B P0C869 1/20 0.50
AKR1B1 P15121 1/20 0.50
PPARD Q03181 1/20 0.49
FFAR1 O14842 1/20 0.48
PTGS1 P23219 2/20 0.48
ABCC4 O15439 1/20 0.48
LMNA P02545 1/20 0.48
GAA P10253 1/20 0.48
TSHR P16473 1/20 0.48
HTT P42858 1/20 0.48
TBXAS1 P24557 1/20 0.48
KDM4E B2RXH2 1/20 0.47
POLB P06746 1/20 0.47
AKR1C3 P42330 1/20 0.47
AKR1C2 P52895 1/20 0.47
RXRA P19793 1/20 0.46
RXRB P28702 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2628191 0.85 PLA2G4B (0.55) CA2CAMK2APLA2G4BFFAR1LMNA
SCHEMBL2628195 0.85 PLA2G4B (0.55) CA2CAMK2APLA2G4BFFAR1LMNA
SCHEMBL11683055 0.83 PLA2G4B (0.61) CA2CAMK2ASRD5A2PLA2G4BAKR1B1
SCHEMBL11155906 0.82 CA2 (0.54) CA2CAMK2ASRD5A2PLA2G4BAKR1B1
SCHEMBL11684213 0.82 PLA2G4B (0.69) CA2CAMK2APLA2G4BAKR1B1FFAR1
SCHEMBL9832704 0.82 ALOX15 (0.63) CA2CAMK2ASRD5A2PLA2G4BAKR1B1
SCHEMBL503308 0.80 PLA2G4B (0.58) CA2CAMK2APLA2G4BPOLBRXRA
SCHEMBL11351141 0.80 CA2 (0.52) CA2CAMK2ASRD5A2PLA2G4BAKR1B1
SCHEMBL7469409 0.80 PPARD (0.53) CA2CAMK2ASRD5A2PLA2G4BAKR1B1
SCHEMBL11596764 0.79 NR4A2 (0.54) PLA2G4BFFAR1LMNATBXAS1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0028422-B1 PROCESS FOR PREPARING ALCOHOLS FROM CARBOXYLIC ACIDS AND PROCESS FOR PREPARING CARBOXYLIC ACIDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-10-05 EP disclosed
US-4317918-A Process for preparing alcohols SUMITOMO CHEMICAL CO., LTD. (JP) 1982-03-02 US disclosed
EP-0028422-A1 Process for preparing alcohols from carboxylic acids and process for preparing carboxylic acids SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-05-13 EP disclosed