Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KLK7 | P49862 | 2/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | CCKAR | P32238 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364118 | 0.94 | ALOX15 (0.43) | MAPK1ITGB3ITGA2BALOX15HTT | |
| SCHEMBL7163527 | 0.94 | MAPT (0.46) | MAPTKLK7KLK5MAPK1POLB | |
| SCHEMBL7361913 | 0.92 | ALOX15 (0.40) | MAPK1ITGB3ITGA2BALOX15HTT | |
| SCHEMBL7479315 | 0.91 | ALOX15 (0.41) | MAPK1ITGB3ALOX15HTTHSD17B10 | |
| SCHEMBL7363235 | 0.89 | KLK5 (0.42) | KLK7KLK5ALOX15HSD17B10IDO1 | |
| SCHEMBL7169944 | 0.86 | IDO1 (0.48) | ITGB3ITGA2BIDO1TDO2CTSL | |
| SCHEMBL7478564 | 0.86 | ALOX15 (0.44) | MAPTMAPK1ALOX15HTTHSD17B10 | |
| SCHEMBL7364535 | 0.86 | ALOX15 (0.41) | MAPTMAPK1ITGB3ITGA2BALOX15 | |
| SCHEMBL7374585 | 0.86 | MMP2 (0.44) | MAPTMAPK1ITGB3ITGA2BALOX15 | |
| SCHEMBL7169155 | 0.85 | ITGB3 (0.46) | ITGB3ITGA2BIDO1TDO2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0964856-B1 | BICYCLIC AMINO ACIDS | MERCK PATENT GMBH (DE) | 2002-10-09 | — | — | EP | disclosed |