Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.36 |
| ▸ | ORAI2 | Q96SN7 | 2/20 | 0.36 |
| ▸ | ORAI3 | Q9BRQ5 | 2/20 | 0.36 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1677080 | 0.86 | PCSK9 (0.42) | ALDH1A1TSHRHPGDMEN1ALOX12 | |
| SCHEMBL1235485 | 0.83 | ALDH1A1 (0.50) | ALDH1A1TSHRHPGDMEN1ALOX12 | |
| SCHEMBL28726874 | 0.79 | LMNA (0.42) | ALDH1A1TSHRHPGDMEN1ALOX12 | |
| Water SCHEMBL27733082 | 0.78 | ALDH1A1 (0.39) | ALDH1A1TSHRHPGDMEN1ALOX12 | |
| SCHEMBL7449530 | 0.77 | ALDH1A1 (0.47) | ALDH1A1TSHRHPGDKDM4ETDP1 | |
| SCHEMBL9160020 | 0.75 | KDM4E (0.32) | ALDH1A1TSHRHPGDMEN1ALOX12 | |
| SCHEMBL907509 | 0.75 | TSHR (0.40) | ALDH1A1TSHRHPGDMEN1ALOX12 | |
| SCHEMBL7796509 | 0.71 | MEN1 (0.42) | ALDH1A1TSHRHPGDMEN1ALOX12 | |
| SCHEMBL7376855 | 0.71 | CA4 (0.39) | ALDH1A1TSHRHPGDMEN1ALOX12 | |
| SCHEMBL2199544 | 0.70 | CYP1A2 (0.50) | ALDH1A1TSHRHPGDMEN1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122094292-A | Composite film, preparation method thereof and solar cell module containing composite film | — | 2026-05-26 | — | — | CN | disclosed |
| CN-114831977-B | Application of benzoic acid derivative as TRPM2 protein inhibitor | 北京大学 | 2023-12-19 | — | — | CN | disclosed |
| CN-112107542-A | Has tumor pH and H2O2Multifunctional polymer micelle with specific activated antitumor activity and preparation method thereof | 西北师范大学 | 2020-12-22 | — | — | CN | disclosed |
| US-20170342025-A1 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | THE UNIVERSITY OF BATH (GB) | 2017-11-30 | — | — | US | disclosed |
| EP-2729150-B1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME (US) | 2016-09-14 | — | — | EP | disclosed |
| US-9161924-B2 | Factor IXa inhibitors | MERCK SHARP & DOHME CORP. (US) | 2015-10-20 | — | — | US | disclosed |
| CN-104478904-A | Anthracene-ring bitriazol-cupric tetrafluoroborate complex capable of catalyzing 4-tert-butyl phenylboronic acid and preparation method thereof | UNIV TIANJIN NORMAL | 2015-04-01 | — | — | CN | disclosed |
| CN-104478904-A | Anthracene-ring bitriazol-cupric tetrafluoroborate complex capable of catalyzing 4-tert-butyl phenylboronic acid and preparation method thereof | UNIV TIANJIN NORMAL | 2015-04-01 | — | — | CN | disclosed |
| US-20140219989-A1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME LLC | 2014-08-07 | — | — | US | disclosed |
| EP-2729150-A2 | FACTOR IXA INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2014-05-14 | — | — | EP | disclosed |
| EP-1888566-A1 | 2-[(ISOQUINOLIN-3-CARBONYL)AMINO]-PROPIONIC ACID DERIVATIVES AS INHIBITORS OF FACTORS XI AND IX FOR THE TREATMENT OF THROMBOSIS | Transtech Pharma, Inc. (US) | 2008-02-20 | — | — | EP | disclosed |
| US-20070254916-A1 | Aryl and heteroaryl compounds, compositions, and methods of use | MJALLI ADNAN M | 2007-11-01 | — | — | US | disclosed |
| US-7208601-B2 | Aryl and heteroaryl compounds, compositions, and methods of use | TRANSTECH PHARMA, LLC | 2007-04-24 | — | — | US | disclosed |
| WO-2006093823-A1 | 2- [ ISOQUINOLIN-S - CARBONYL ) AMINO] -PROPIONIC ACID DERIVATIVES AS INHIBITORS OF FACTORS XI AND IX FOR THE TREATMENT OF THROMBOSIS | TRANSTECH PHARMA, INC. (US) | 2006-09-08 | — | — | WO | disclosed |
| EP-1660439-A2 | ARYL AND HETEROARYL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | Transtech Pharma, Inc. (US) | 2006-05-31 | — | — | EP | disclosed |
| US-6930131-B2 | Aryl substituted 3-ethoxy phenyl trifluoromethane sulfonamides for the treatment of non-insulin dependent diabetes mellitus (NIDDM) | WYETH (US) | 2005-08-16 | — | — | US | disclosed |
| US-20050171148-A1 | Aryl and heteroaryl compounds, compositions, methods of use | TRANSTECH PHARMA, LLC | 2005-08-04 | — | — | US | disclosed |
| US-20050059705-A1 | Aryl and heteroaryl compounds, compositions, and methods of use | VTVX HOLDINGS I LLC | 2005-03-17 | — | — | US | disclosed |
| WO-2005014533-A2 | ARYL AND HETEROARYL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | TRANSTECH PHARMA, INC. (US) | 2005-02-17 | — | — | WO | disclosed |
| US-20030203941-A1 | Substituted phenyl compounds for the treatment of non-insulin dependent diabetes mellitus | WYETH (US) | 2003-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140219989-A1 | FACTOR IXA INHIBITORS | F9, F12, F11 | ALDH1A1 1489/4885TSHR 1691/4885HPGD 1452/4885 |
| US-20030203941-A1 | Substituted phenyl compounds for the treatment of non-insulin dependent diabetes mellitus | GPR119, INSR, SLC5A1 | ALDH1A1 536/4885TSHR 605/4885HPGD 3774/4885 |
| US-20170342025-A1 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | ZYX, MPO, CFB | ALDH1A1 1734/4885TSHR 4667/4885HPGD 1671/4885 |
| US-20050059705-A1 | Aryl and heteroaryl compounds, compositions, and methods of use | TFPI, F3, F2 | ALDH1A1 2886/4885TSHR 867/4885HPGD 774/4885 |
| US-20070254916-A1 | Aryl and heteroaryl compounds, compositions, and methods of use | TFPI, F9, F3 | ALDH1A1 2892/4885TSHR 912/4885HPGD 997/4885 |
| US-20050171148-A1 | Aryl and heteroaryl compounds, compositions, methods of use | TFPI, F3, F2 | ALDH1A1 2897/4885TSHR 970/4885HPGD 921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.