Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 10/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 10/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 10/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462278 | 0.87 | ADRA1D (0.44) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL7472063 | 0.87 | ADRA1D (0.44) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL7461467 | 0.85 | DRD2 (0.45) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL7467112 | 0.82 | HTR1A (0.51) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL7467130 | 0.82 | HTR1A (0.51) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL6977646 | 0.79 | ADRA1D (0.58) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL7684196 | 0.76 | ADRA1D (0.71) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL7684734 | 0.76 | ADRA1D (0.71) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL6196452 | 0.74 | HTR1A (0.51) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL6197421 | 0.74 | HTR1A (0.51) | ADRA1DADRA1AADRA1BHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876372-B1 | HETEROARYLCARBOXAMIDE DERIVATIVES | KNOLL GMBH (DE) | 2002-03-06 | — | — | EP | claimed |
| US-6107310-A | PSYCHOLOGICAL DISORDERS | KNOLL AKTIENGESELLSCHAFT (DE) | 2000-08-22 | — | — | US | claimed |
| EP-0876372-B1 | HETEROARYLCARBOXAMIDE DERIVATIVES | KNOLL GMBH (DE) | 2002-03-06 | — | — | EP | disclosed |
| US-6107310-A | PSYCHOLOGICAL DISORDERS | KNOLL AKTIENGESELLSCHAFT (DE) | 2000-08-22 | — | — | US | disclosed |