Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477511 | 0.87 | ALOX5 (0.48) | TSHRALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL28750014 | 0.87 | TSHR (0.50) | PDE3BPDE3ATSHRALDH1A1KDM4E | |
| SCHEMBL7481382 | 0.86 | ALDH1A1 (0.46) | PDE3BPDE3ATSHRALDH1A1KDM4E | |
| SCHEMBL7474003 | 0.85 | HRH3 (0.60) | GABRA1GABRB1GABRA3GABRB2PDE3B | |
| SCHEMBL7477279 | 0.84 | PDGFRB (0.49) | TSHRALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL7478060 | 0.84 | CYP11B1 (0.43) | TSHRALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL7481943 | 0.83 | SMN1; SMN2 (0.46) | TSHRALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL7482853 | 0.82 | HRH3 (0.50) | PDE3BPDE3ATSHRALDH1A1KDM4E | |
| SCHEMBL7471932 | 0.78 | HSD17B10 (0.39) | PDE3BPDE3ATSHRALDH1A1KDM4E | |
| SCHEMBL2311400 | 0.77 | GABRA1 (0.56) | GABRA1GABRB1GABRA3GABRB2PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210343-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | AstraZeneca AB (SE) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001012187-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2001-02-22 | — | — | WO | disclosed |