Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471586 | 0.89 | KDM4E (0.39) | HSD17B10USP2GAAKDM4EALDH1A1 | |
| SCHEMBL7477511 | 0.79 | ALOX5 (0.48) | HSD17B10GAAMEN1KMT2AKDM4E | |
| SCHEMBL28750014 | 0.78 | TSHR (0.50) | HSD17B10GAAMEN1KMT2AKDM4E | |
| SCHEMBL7469855 | 0.78 | GABRA1 (0.46) | HSD17B10GAAMEN1KMT2AKDM4E | |
| SCHEMBL7481382 | 0.78 | ALDH1A1 (0.46) | HSD17B10GAAMEN1KMT2ACYP1A2 | |
| SCHEMBL7474003 | 0.77 | HRH3 (0.60) | HSD17B10GAAMEN1KMT2AKDM4E | |
| SCHEMBL7477279 | 0.76 | PDGFRB (0.49) | HSD17B10GAAMEN1KMT2AKDM4E | |
| SCHEMBL27583573 | 0.76 | BRD4 (0.36) | GAAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL7478060 | 0.75 | CYP11B1 (0.43) | HSD17B10GAAMEN1KMT2AKDM4E | |
| SCHEMBL7481943 | 0.75 | SMN1; SMN2 (0.46) | HSD17B10MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210343-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | AstraZeneca AB (SE) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001012187-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2001-02-22 | — | — | WO | disclosed |