SCHEMBL7477592

SCHEMBL7477592

CCOC(=O)c1scc(SC)c1OS(=O)(=O)Cl

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.37
MAPT P10636 7/20 0.36
GSK3B P49841 1/20 0.36
THRB P10828 1/20 0.36
NPSR1 Q6W5P4 3/20 0.36
ALDH1A1 P00352 5/20 0.35
KMT2A Q03164 3/20 0.35
MEN1 O00255 1/20 0.35
TSHR P16473 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TP53 P04637 2/20 0.35
POLB P06746 1/20 0.35
GAA P10253 3/20 0.35
HSD17B10 Q99714 1/20 0.35
HPGD P15428 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
PPARG P37231 1/20 0.34
NCOA2 Q15596 1/20 0.34
NCOA1 Q15788 1/20 0.34
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7471848 0.90 STS (0.36) LMNAMAPTALDH1A1KMT2ATSHR
SCHEMBL7471177 0.85 KDM4E (0.40) LMNAMAPTNPSR1KMT2ATSHR
SCHEMBL7466240 0.83 MAPT (0.39) LMNAMAPTGSK3BTHRBALDH1A1
SCHEMBL7470040 0.82 ALDH1A1 (0.41) LMNAMAPTGSK3BTHRBNPSR1
SCHEMBL7472780 0.82 MAPT (0.39) LMNAMAPTGSK3BTHRBNPSR1
SCHEMBL7469012 0.82 MAPT (0.41) LMNAMAPTGSK3BTHRBNPSR1
SCHEMBL7473950 0.82 LMNA (0.32) LMNANPSR1ALDH1A1HPGDCA1
SCHEMBL7470407 0.81 MAPT (0.45) LMNAMAPTTHRBNPSR1ALDH1A1
SCHEMBL7031264 0.81 MAPT (0.40) LMNAMAPTGSK3BTHRBNPSR1
SCHEMBL7463597 0.80 MAPT (0.44) LMNAMAPTTHRBNPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0859774-B1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 2002-04-03 EP disclosed
EP-0859774-A1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 1998-08-26 EP disclosed
WO-1997016449-A1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-05-09 WO disclosed