Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1C | P00326 | 2/20 | 0.53 |
| ▸ | ADH1A | P07327 | 2/20 | 0.53 |
| ▸ | ADH1B | P00325 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | PHGDH | O43175 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7498978 | 0.79 | ADH1C (0.56) | ADH1CADH1AADH1B | |
| SCHEMBL27605000 | 0.78 | — | — | |
| SCHEMBL5127609 | 0.74 | ADH1B (0.46) | ADH1CADH1AADH1B | |
| SCHEMBL7471560 | 0.72 | ADH1B (0.47) | ADH1CADH1AADH1B | |
| SCHEMBL9462559 | 0.72 | ADH1A (0.95) | ADH1CADH1AADH1B | |
| SCHEMBL5123903 | 0.70 | ADH1C (0.58) | ADH1CADH1AADH1B | |
| SCHEMBL4274516 | 0.70 | FAAH (0.38) | FAAHPHGDHMGLL | |
| SCHEMBL4274519 | 0.70 | FAAH (0.38) | FAAHPHGDHMGLL | |
| SCHEMBL9463243 | 0.70 | ADH1A (1.00) | ADH1CADH1AADH1B | |
| Hydrochloric Acid SCHEMBL5128398 | 0.69 | ADH1B (0.56) | ADH1CADH1AADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183245-A4 | SELECTIVE NPY (Y5) ANTAGONISTS | SYNAPTIC PHARMA CORP (US) | 2002-10-02 | — | — | EP | disclosed |
| EP-1183245-A1 | SELECTIVE NPY (Y5) ANTAGONISTS | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000064880-A1 | SELECTIVE NPY (Y5) ANTAGONISTS | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2000-11-02 | — | — | WO | disclosed |