Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 4/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.38 |
| ▸ | CASR | P41180 | 3/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664584 | 0.91 | CCR5 (0.42) | ITGB3ITGAVITGA2BOPRM1CCR5 | |
| SCHEMBL7462626 | 0.87 | ITGB3 (0.46) | ITGB3ITGAVITGA2BCCR2OPRM1 | |
| SCHEMBL7470398 | 0.83 | ITGB3 (0.51) | ITGB3ITGAVITGA2BCCR2BTK | |
| SCHEMBL7048411 | 0.83 | ITGB3 (0.51) | ITGB3ITGAVITGA2BCCR2BTK | |
| SCHEMBL7465258 | 0.82 | ITGB3 (0.51) | ITGB3ITGAVITGA2BCCR2BTK | |
| SCHEMBL7462239 | 0.81 | ITGB3 (0.49) | ITGB3ITGAVITGA2BCCR2CASR | |
| SCHEMBL7468616 | 0.80 | ITGB3 (0.47) | ITGB3ITGAVITGA2BCCR2BTK | |
| SCHEMBL382702 | 0.78 | ITGB3 (0.46) | ITGB3ITGAVITGA2BCASR | |
| SCHEMBL382545 | 0.78 | ITGB3 (0.46) | ITGB3ITGAVITGA2BCASR | |
| SCHEMBL7655428 | 0.77 | HPGDS (0.44) | ITGB3ITGAVITGA2BCASRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |