Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469972 | 0.92 | EGFR (0.51) | PIK3CDPIK3R1EGFRBRD4ERBB2 | |
| SCHEMBL7470043 | 0.82 | HTR1A (0.44) | PIK3CDPIK3R1EGFRBRD4ERBB2 | |
| SCHEMBL7463424 | 0.81 | EGFR (0.50) | PIK3CDPIK3R1EGFRBRD4ERBB2 | |
| SCHEMBL7470174 | 0.81 | HTT (0.57) | PIK3CDPIK3R1EGFRBRD4ERBB2 | |
| SCHEMBL9921372 | 0.80 | HTT (0.62) | PIK3CDPIK3R1EGFRBRD4ERBB2 | |
| SCHEMBL7474381 | 0.76 | PDE5A (0.61) | KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL7461677 | 0.75 | HTR1A (0.46) | EGFRBRD4ERBB2ERBB4KMT2A | |
| SCHEMBL7468656 | 0.75 | HTT (0.67) | EGFRERBB2KMT2ANTRK1MAPK1 | |
| SCHEMBL7471400 | 0.74 | MAPT (0.42) | PIK3CDPIK3R1EGFRBRD4ERBB2 | |
| SCHEMBL7474806 | 0.73 | EGFR (0.52) | EGFRBRD4ERBB2ERBB4NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |