Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469725 | 0.89 | ALDH1A1 (0.50) | EGFRACHEAURKARPS6KB1MAPT | |
| SCHEMBL7461647 | 0.89 | EGFR (0.48) | EGFRAURKARPS6KB1MAPTWDR5 | |
| SCHEMBL7468826 | 0.86 | EGFR (0.56) | EGFRMAPTHTR6 | |
| SCHEMBL7466276 | 0.86 | MAPK1 (0.56) | EGFRACHEMAPTKMT2A | |
| SCHEMBL7469783 | 0.84 | ALDH1A1 (0.48) | EGFRMAPTWDR5KMT2AHTR6 | |
| SCHEMBL7470206 | 0.83 | EGFR (0.52) | EGFRMAPTHTR6 | |
| SCHEMBL7470232 | 0.82 | CLK4 (0.46) | EGFRSRCAURKARPS6KB1AURKB | |
| SCHEMBL7469830 | 0.82 | HTR6 (0.44) | EGFRACHEMAPTWDR5KMT2A | |
| SCHEMBL7475684 | 0.82 | EGFR (0.53) | EGFRMAPTWDR5KMT2AHTR6 | |
| SCHEMBL7474960 | 0.82 | MAPT (0.43) | EGFRMAPTWDR5KMT2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |