SCHEMBL7470266

SCHEMBL7470266

CO/N=C(\OCC(=O)OC)C(C)Oc1ccc(Cn2c(=O)cc(C(F)(F)F)n(C)c2=O)c(Cl)c1Cl

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
P2RX3 P56373 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7470272 1.00 P2RX3 (0.32) P2RX3
SCHEMBL7472616 0.86 P2RX3 (0.34) P2RX3
SCHEMBL7468861 0.82 PPARG (0.35) P2RX3
SCHEMBL7471410 0.82 PPARG (0.33) P2RX3
SCHEMBL7466593 0.82 RAB9A (0.34) P2RX3
SCHEMBL7473933 0.80 POLB (0.34) P2RX3
SCHEMBL7470706 0.79 P2RX3 (0.39) P2RX3
SCHEMBL8308815 0.79
SCHEMBL7472788 0.75 RORC (0.42)
SCHEMBL7476563 0.75 LMNA (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0891336-B1 SUBSTITUTED 1-METHYL-3-BENZYLURACILS BASF AG (DE) 2002-06-05 EP disclosed