Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.32 |
| ▸ | CMA1 | P23946 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472616 | 0.88 | P2RX3 (0.34) | POLBP2RX3CMA1HSD17B13 | |
| SCHEMBL7476618 | 0.84 | ACLY (0.37) | POLBMEN1LMNAKMT2ACMA1 | |
| SCHEMBL7472788 | 0.84 | RORC (0.42) | TDP1MEN1LMNAKMT2ARORC | |
| SCHEMBL7476563 | 0.84 | LMNA (0.36) | POLBMEN1LMNAKMT2ACMA1 | |
| SCHEMBL7468861 | 0.80 | PPARG (0.35) | MEN1LMNAKMT2AP2RX3CMA1 | |
| SCHEMBL7471410 | 0.80 | PPARG (0.33) | LMNAP2RX3CMA1HSD17B13 | |
| SCHEMBL7470266 | 0.80 | P2RX3 (0.32) | P2RX3 | |
| SCHEMBL7470272 | 0.80 | P2RX3 (0.32) | P2RX3 | |
| SCHEMBL7470706 | 0.79 | P2RX3 (0.39) | P2RX3 | |
| SCHEMBL7466593 | 0.78 | RAB9A (0.34) | P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891336-B1 | SUBSTITUTED 1-METHYL-3-BENZYLURACILS | BASF AG (DE) | 2002-06-05 | — | — | EP | disclosed |