Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | AVPR1B | P47901 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 2/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8742824 | 0.94 | AVPR1A (0.41) | MAPK1AVPR1ATSHRCYP3A4ALOX15 | |
| SCHEMBL7473645 | 0.86 | AVPR1B (0.48) | AVPR1AAVPR2AVPR1BOXTR | |
| SCHEMBL7472360 | 0.81 | NPSR1 (0.38) | MAPK1AVPR1ATSHRCYP3A4ALOX15 | |
| Trifluoroacetic Acid SCHEMBL8742977 | 0.78 | NPSR1 (0.36) | AVPR1BALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7467560 | 0.74 | NPSR1 (0.38) | AVPR1AAVPR1BMAPTMEN1KMT2A | |
| SCHEMBL9220661 | 0.74 | MAPK1 (0.38) | MAPK1TSHRCYP3A4ALDH1A1MEN1 | |
| SCHEMBL7473790 | 0.72 | LMNA (0.46) | MAPK1TSHRALDH1A1MAPTKMT2A | |
| SCHEMBL7467489 | 0.72 | AVPR1B (0.39) | MAPK1AVPR1ATSHRCYP3A4ALOX15 | |
| SCHEMBL7477246 | 0.72 | NPSR1 (0.39) | MAPK1AVPR1ATSHRCYP3A4ALOX15 | |
| Water SCHEMBL8590384 | 0.72 | LMNA (0.45) | MAPK1TSHRALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687251-B1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI SYNTHELABO (FR) | 2002-02-27 | — | — | EP | disclosed |
| WO-1995018105-A1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI (FR) | 1995-07-06 | — | — | WO | disclosed |