Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 8/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | RHEB | Q15382 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7461866 | 0.93 | MEN1 (0.48) | NAMPTMEN1LMNAKMT2AMAPT | |
| SCHEMBL7468043 | 0.85 | MAPT (0.48) | NAMPTMEN1LMNAKMT2AMAPT | |
| SCHEMBL4456863 | 0.84 | GABRA5 (0.53) | LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL7457276 | 0.81 | MAPT (0.47) | MEN1LMNAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7460793 | 0.81 | MAPT (0.51) | MEN1LMNAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7472590 | 0.81 | HDAC6 (0.54) | MAPTSMN1; SMN2KDM4EHDAC1HDAC8 | |
| SCHEMBL7468729 | 0.80 | MAPT (0.46) | MEN1LMNAKMT2AMAPTMAPK1 | |
| SCHEMBL7468517 | 0.80 | HDAC6 (0.52) | MEN1KMT2AMAPTSMN1; SMN2HDAC1 | |
| SCHEMBL7466124 | 0.79 | CMA1 (0.46) | MAPTHDAC1HDAC8HDAC6 | |
| SCHEMBL7463809 | 0.79 | TP53 (0.51) | LMNAMAPTMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |