Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 9/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430382 | 0.90 | TMEM97 (0.47) | TMEM97SIGMAR1MEN1KMT2AHTR6 | |
| SCHEMBL8157601 | 0.75 | DRD2 (0.48) | TMEM97SIGMAR1 | |
| SCHEMBL7030804 | 0.75 | DRD2 (0.56) | — | |
| SCHEMBL7030108 | 0.75 | DRD2 (0.48) | TMEM97SIGMAR1 | |
| SCHEMBL7025402 | 0.75 | DRD2 (0.56) | — | |
| SCHEMBL6816670 | 0.75 | DRD2 (0.48) | TMEM97SIGMAR1 | |
| SCHEMBL4885848 | 0.74 | CXCR4 (0.51) | CXCR4 | |
| SCHEMBL4882675 | 0.74 | CXCR4 (0.62) | CXCR4HTR6 | |
| SCHEMBL14270200 | 0.74 | CXCR4 (0.62) | CXCR4 | |
| SCHEMBL27375281 | 0.73 | ADRA2C (0.45) | CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888319-A1 | SUBSTITUTED 1,2,3,4-TETRAHYDRONAPHTHALENE DERIVATIVES | Astra Aktiebolag (SE) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034883-A1 | SUBSTITUTED 1,2,3,4-TETRAHYDRONAPHTHALENE DERIVATIVES | ASTRA AKTIEBOLAG (SE) | 1997-09-25 | — | — | WO | disclosed |