Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 7/20 | 0.47 |
| ▸ | KCNQ1 | P51787 | 7/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559235 | 0.87 | KCNE1 (0.52) | KCNE1KCNQ1PTPN1ALDH1A1KDM4E | |
| SCHEMBL3589162 | 0.82 | HTR2B (0.46) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL6601951 | 0.81 | MAOB (0.53) | KCNE1KCNQ1ALDH1A1HPGDNPSR1 | |
| Hydrochloric Acid SCHEMBL6559487 | 0.81 | HTR2B (0.45) | ALDH1A1KDM4EMEN1KMT2AHTR1A | |
| SCHEMBL7464900 | 0.77 | KCNE1 (0.52) | KCNE1KCNQ1PTPN1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL6558668 | 0.75 | CA2 (0.37) | KCNE1KCNQ1ALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL6560785 | 0.75 | PARP1 (0.35) | ALDH1A1NPSR1HTR1AHTR2BSIGMAR1 | |
| SCHEMBL7910194 | 0.74 | NCF1 (0.38) | KCNE1KCNQ1PTPN1ALDH1A1KDM4E | |
| SCHEMBL7479500 | 0.74 | HTR2C (0.42) | KDM4EMEN1KMT2AHTR1AHTR2B | |
| SCHEMBL6024969 | 0.73 | BACE1 (0.37) | ALDH1A1HTR2BHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0905131-B1 | Sulfonamid-substituted chromans, process for their preparation, their use as medicine, and pharmaceutical preparation containing them | AVENTIS PHARMA GMBH (DE) | 2002-04-10 | — | — | EP | disclosed |
| US-5955607-A | TREATING CARDIOVASCULAR AND GASTROINTESTINAL DISORDERS | HOECHST MARION ROUSSEL DEUTSCHLAND (DE) | 1999-09-21 | — | — | US | disclosed |
| EP-0905131-A1 | Sulfonamid-substituted chromans, process for their preparation, their use as medicine, and pharmaceutical preparation containing them | Hoechst Marion Roussel Deutschland GmbH (DE) | 1999-03-31 | — | — | EP | disclosed |