Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471994 | 0.91 | KEAP1 (0.47) | KMT2AKEAP1NFE2L2MAPTALDH1A1 | |
| Bromide SCHEMBL7469202 | 0.87 | KMT2A (0.48) | KMT2AMAPTALDH1A1GAAHSP90AA1 | |
| SCHEMBL7532968 | 0.85 | KMT2A (0.46) | KMT2AGLAKEAP1NFE2L2MAPT | |
| SCHEMBL9407963 | 0.83 | MAPT (0.43) | KMT2AGLAMAPTALDH1A1GAA | |
| SCHEMBL7458558 | 0.82 | MAPT (0.45) | KMT2AMAPTALDH1A1GAAHPGD | |
| SCHEMBL8076562 | 0.82 | MAPT (0.52) | KMT2AKEAP1NFE2L2MAPTALDH1A1 | |
| SCHEMBL8076269 | 0.82 | ALDH1A1 (0.42) | KMT2AKEAP1NFE2L2MAPTALDH1A1 | |
| SCHEMBL8076560 | 0.80 | MMP3 (0.42) | KMT2AKEAP1NFE2L2ALDH1A1HSP90AA1 | |
| Bromide SCHEMBL7459708 | 0.79 | HSP90AA1 (0.50) | KMT2AMAPTALDH1A1GAAHSP90AA1 | |
| Bromide SCHEMBL8076530 | 0.77 | KEAP1 (0.46) | KMT2AKEAP1NFE2L2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647628-B1 | Acridinium derivatives and their use in luminescence immunoassays | DADE BEHRING MARBURG GMBH (DE) | 2002-09-11 | — | — | EP | disclosed |
| EP-0257541-B1 | Chemilumuniscent acridine derivatives and their use in luminescence immunoassays | HOECHST AG (DE) | 1996-01-03 | — | — | EP | disclosed |
| EP-0647628-A1 | Acridmium derivatives and their use in luminescence immunoassays | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-04-12 | — | — | EP | disclosed |
| EP-0602524-A1 | Chemiluminescence marked sequences and their use in sequence testing | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-22 | — | — | EP | disclosed |
| EP-0257541-A2 | Chemilumuniscent acridine derivatives and their use in luminescence immunoassays | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-03-02 | — | — | EP | disclosed |