Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 5/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BMP1 | P13497 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 2/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8076269 | 0.94 | ALDH1A1 (0.42) | KEAP1NFE2L2ALDH1A1F2HPGD | |
| Bromide SCHEMBL8076287 | 0.89 | KEAP1 (0.43) | MMP3KEAP1NFE2L2ALDH1A1F2 | |
| SCHEMBL8471272 | 0.89 | ALDH1A1 (0.46) | MMP3KEAP1NFE2L2ALDH1A1F2 | |
| SCHEMBL9407911 | 0.86 | LMNA (0.49) | KEAP1NFE2L2ALDH1A1KMT2ALMNA | |
| SCHEMBL8079548 | 0.86 | ALDH1A1 (0.38) | MMP3KEAP1NFE2L2ALDH1A1F2 | |
| SCHEMBL7471994 | 0.85 | KEAP1 (0.47) | KEAP1NFE2L2ALDH1A1F2HPGD | |
| Bromide SCHEMBL8076530 | 0.85 | KEAP1 (0.46) | KEAP1NFE2L2ALDH1A1F2HPGD | |
| SCHEMBL8076290 | 0.83 | KEAP1 (0.40) | KEAP1NFE2L2LMNATP53TOP2A | |
| SCHEMBL8469225 | 0.83 | ALDH1A1 (0.48) | KEAP1NFE2L2ALDH1A1F2HPGD | |
| SCHEMBL8080887 | 0.81 | LMNA (0.44) | KEAP1NFE2L2ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330050-B1 | Special chemiluminescent acridine derivatives and their use in luminescence immunoassays | DADE BEHRING MARBURG GMBH (DE) | 2000-08-23 | — | — | EP | disclosed |
| EP-0602524-A1 | Chemiluminescence marked sequences and their use in sequence testing | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-22 | — | — | EP | disclosed |
| EP-0330050-A2 | Special chemiluminescent acridine derivatives and their use in luminescence immunoassays | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-30 | — | — | EP | disclosed |