Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475318 | 0.86 | MAPK14 (0.42) | KDM4ETSHRKMT2AALDH1A1TDP1 | |
| SCHEMBL7475041 | 0.85 | F7 (0.42) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL7474375 | 0.81 | MAPK14 (0.43) | KDM4ETSHRMEN1KMT2AMAPT | |
| SCHEMBL7469629 | 0.81 | KMT2A (0.44) | KDM4ETSHRKMT2AALDH1A1PKM | |
| SCHEMBL7471290 | 0.81 | ALDH1A1 (0.41) | KDM4ETSHRALDH1A1ATMNPSR1 | |
| SCHEMBL7477253 | 0.77 | KDM4E (0.49) | KDM4EALDH1A1HSP90AA1ATMNPSR1 | |
| SCHEMBL7473148 | 0.76 | MAPK14 (0.44) | TSHRALDH1A1MAPTGAAMAPK14 | |
| SCHEMBL7473758 | 0.76 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1HSP90AA1ATM | |
| SCHEMBL7471841 | 0.76 | MAPK14 (0.44) | ALDH1A1HSP90AA1ATMNPSR1TLR9 | |
| SCHEMBL7474779 | 0.76 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1HSP90AA1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077701-A4 | ANTI-VIRAL COMPOUNDS | LILLY CO ELI (US) | 2002-03-20 | — | — | EP | disclosed |
| EP-1077701-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059587-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-11-25 | — | — | WO | disclosed |