Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | S100B | P04271 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474779 | 0.90 | ALDH1A1 (0.45) | ALDH1A1MITFHSP90AA1HTTATM | |
| SCHEMBL7477253 | 0.86 | KDM4E (0.49) | ALDH1A1MITFHSP90AA1HTTATM | |
| SCHEMBL7471841 | 0.85 | MAPK14 (0.44) | ALDH1A1MITFHSP90AA1HTTATM | |
| SCHEMBL11810208 | 0.83 | ALDH1A1 (0.52) | ALDH1A1MITFHSP90AA1HTTATM | |
| SCHEMBL7471112 | 0.82 | ALDH1A1 (0.49) | ALDH1A1HTTNPSR1MAPTLMNA | |
| SCHEMBL7466640 | 0.82 | LMNA (0.59) | ALDH1A1HTTMAPTLMNAPOLB | |
| SCHEMBL7470913 | 0.82 | HTT (0.41) | ALDH1A1HTTMAPTLMNAPOLB | |
| SCHEMBL7475152 | 0.81 | MAPK14 (0.44) | ALDH1A1HTTALOX15MAPTPOLB | |
| SCHEMBL7476225 | 0.79 | CYP11B1 (0.41) | HTTMAPTLMNAKMT2A | |
| SCHEMBL11809684 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MITFHSP90AA1HTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077701-A4 | ANTI-VIRAL COMPOUNDS | LILLY CO ELI (US) | 2002-03-20 | — | — | EP | disclosed |
| EP-1077701-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059587-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-11-25 | — | — | WO | disclosed |