Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F12 | P00748 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471362 | 0.87 | LTA4H (0.40) | MAPK14F2F12LTA4HRAB9A | |
| SCHEMBL7470949 | 0.86 | KDM4E (0.49) | MAPK14LTA4HKDM4ELMNAPOLB | |
| SCHEMBL7474375 | 0.86 | MAPK14 (0.43) | MAPK14RAB9AKDM4ENPC1LMNA | |
| SCHEMBL7471841 | 0.85 | MAPK14 (0.44) | MAPK14RAB9ANPC1LMNAPOLB | |
| SCHEMBL7473148 | 0.85 | MAPK14 (0.44) | MAPK14RAB9ANPC1LMNAPOLB | |
| SCHEMBL7471290 | 0.84 | ALDH1A1 (0.41) | MAPK14KDM4EALDH1A1ATMNPSR1 | |
| SCHEMBL7475041 | 0.81 | F7 (0.42) | F2F12RAB9ANPC1POLB | |
| SCHEMBL7469629 | 0.78 | KMT2A (0.44) | RAB9AKDM4ENPC1LMNAALDH1A1 | |
| SCHEMBL7477253 | 0.78 | KDM4E (0.49) | MAPK14KDM4ELMNAPOLBALDH1A1 | |
| SCHEMBL7475152 | 0.78 | MAPK14 (0.44) | MAPK14RAB9AKDM4ENPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077701-A4 | ANTI-VIRAL COMPOUNDS | LILLY CO ELI (US) | 2002-03-20 | — | — | EP | disclosed |
| EP-1077701-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059587-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-11-25 | — | — | WO | disclosed |