Water

Water

SCHEMBL747141

O.O.O.O=[N+]([O-])[O-].O=[N+]([O-])[O-].O=[N+]([O-])[O-].[In+3]

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 known ✓ O00255 1/20 0.67
KMT2A Q03164 1/20 0.67
CA5A P35218 1/20 0.46
CA5B Q9Y2D0 1/20 0.46
TSHR P16473 3/20 0.39
ALDH1A1 P00352 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
HPGD P15428 1/20 0.36
HIF1A Q16665 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL29168442 1.00 MEN1 (0.67) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL892502 1.00 MEN1 (0.67) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL744582 1.00 MEN1 (0.67) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL28339176 1.00 MEN1 (0.67) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL8021457 1.00 MEN1 (0.67) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL2590832 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL28398822 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL28478211 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR
SCHEMBL50075 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL10566608 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117160443-A Indium-manganese composite catalyst for preparing methanol by carbon dioxide hydrogenation, preparation method and application thereof 南京理工大学 2023-12-05 CN claimed
CN-112076793-B In-MOF material based on tricarboxylic acid ligand, preparation method and application 西安工程大学 2022-12-09 CN claimed
CN-112076795-B Preparation method and application of magnetic In-MOF-based photocatalyst 西安工程大学 2022-11-29 CN claimed
CN-113509932-A Semiconductor photocatalyst and preparation method thereof 电子科技大学长三角研究院(湖州) 2021-10-19 CN claimed
CN-112076795-A Preparation method and application of magnetic In-MOF-based photocatalyst 西安工程大学 2020-12-15 CN claimed
CN-112076793-A In-MOF material based on tricarboxylic acid ligand, preparation method and application 西安工程大学 2020-12-15 CN claimed
CN-108283930-B Non-equal-ratio sulfur indium cadmium composite photocatalyst, preparation method and application 江苏大学 2020-07-31 CN claimed
CN-103537312-A Preparation and application of indium-nitrogen codoped ZnO nano photocatalytic material UNIV JIANGNAN 2014-01-29 CN claimed
US-7147805-B2 Composition for forming a transparent conducting film, solution for forming a transparent conducting film and method of forming a transparent conducting film NICHIA CORPORATION (JP) 2006-12-12 US claimed
CN-122070994-A Nanoscale cobalt-based catalyst and preparation method and application thereof 中国石油天然气股份有限公司 2026-05-22 CN disclosed
EP-4628556-A2 POLISHING METHOD AND POLISHING COMPOSITION Fujimi Incorporated (JP) 2025-10-08 EP disclosed
CN-116062772-B Foam molecular sieve and normal paraffin hydroisomerization catalyst prepared from same 汕头大学 2025-03-28 CN disclosed
CN-112514078-B Coating liquid for forming metal oxide film, oxide insulator film, field effect transistor, display element, image display device, and system 株式会社理光 2025-02-11 CN disclosed
US-12198841-B2 Magnetic powder, manufacturing method of magnetic powder, and magnetic recording medium FUJIFILM CORPORATION (JP) 2025-01-14 US disclosed
US-5112783-A Containing chloride and/or nitrate, cubic structure UBE INDUSTRIES, LTD. (JP) 1992-05-12 US disclosed
US-5089459-A Mixture of crystalline aluminum silicate zeolites substituted by alkali metals and refractory oxides supporting platinum, tin and/or indium TEIJIN PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-02-18 US disclosed
US-5032561-A Alumina-silica zeolite TEIJIN PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-07-16 US disclosed
EP-0390058-A1 Catalyst composition, process for cracking non-aromatic hydrocarbons and process for isomerizing C8 aromatic hydrocarbons TEIJIN LIMITED (JP) 1990-10-03 EP disclosed
EP-0361424-A2 Catalyst composition, process for cracking non-aromatic hydrocarbons and process for isomerizing C8-aromatic hydrocarbons TEIJIN LIMITED (JP) 1990-04-04 EP disclosed
EP-0061689-B1 RADIATION SENSITIVE POLYMER MATERIALS Hitachi, Ltd. (JP) 1986-08-27 EP disclosed